Table 3.
Skin Irritation Scorns Following Transdsrmal Patch Administration
| Rabbit No. | Group I (without any drug) | Group II (A1) | Group III (Formalin) | |||
|---|---|---|---|---|---|---|
| Erythemaa | Edemab | Erythema | Edema | Erythema | Edema | |
| 1 | 0 | 1 | 0 | 0 | 3 | 2 |
| 2 | 1 | 0 | 0 | 1 | 3 | 1 |
| 3 | 0 | 1 | 1 | 1 | 3 | 2 |
| Average ±S.D | 0.34±0.58* | 0.67±0.58* | 0.34±0.58* | 0.67±0.58* | 3±0 | 1.67±0.58 |
*
p<0.05, significant compared with formalin.
a
: Erythema scale: 0, none; 1, slight; 2, well defined; 3, moderate; and 4, scar formation.
b
: Edema scale: 0, none; 1, slight; 2, well defined; 3, moderate; and 4, severe.