Table 1.
Ingredients of bilayered buccal tablets of sumatriptan succinate.
| Formulationcode | Sumatriptan succinate (mg) | HPMC K4M (mg) | HPMC K15M (mg) | Carbopol 934P(mg) | Aspartame (mg) | MCC (mg) | Magnesium stearate (mg) | Ethyl cellulose (mg) |
|---|---|---|---|---|---|---|---|---|
| T1 | 10 | 25 | 75 | 1 | 18 | 2 | 20 | |
| T2 | 10 | 50 | 50 | 1 | 18 | 2 | 20 | |
| T3 | 10 | 75 | 25 | 1 | 18 | 2 | 20 | |
| T4 | 10 | 25 | 75 | 1 | 18 | 2 | 20 | |
| T5 | 10 | 50 | 50 | 1 | 18 | 2 | 20 | |
| T6 | 10 | 75 | 25 | 1 | 18 | 2 | 20 |