Table 1.
Mean (± SD) body weight, organ weight and serum biochemical data in control and LC rats (n=5, respectively).
| Parameters | Control | Liver Cirrhosis |
|---|---|---|
| Initial body weight (g) | 189±14.4 | 192±11.5 |
| Final body weight (g) | 372±28.2 | 274±25.6** |
| Liver weight (g) | 13.8±1.9 | 6.2±1.5** |
| Liver weight (% of body weight) | 3.7±0.53 | 2.2±0.36** |
| Kidney weight (g) | 2.8±0.29 | 2.1±0.27** |
| Kidney weight (% of body weight) | 0.75±0.062 | 0.79±0.092 * |
| Spleen weight (g) | 0.85±0.077 | 1.3±0.29** |
| Spleen weight (% of body weight) | 0.23±0.029 | 0.47±0.095** |
| Serum | ||
| Total proteins (g·dl−1) | 6.46±0.60 | 4.01±0.45** |
| Albumin (g·dl−1) | 3.41±0.49 | 2.27±0.44** |
| GOT (IU·l−1) | 99.5±16.3 | 183.6±21.6** |
| GPT (IU·l−1) | 45.4±9.8 | 102.5±22.5** |
| Total bilirubin (mg·dl−1) | 0.29±0.023 | 1.13±0.15** |
| Direct bilirubin (mg·dl−1) | 0.046±0.0095 | 0.252±0.0554** |
*
P<0.05,
**
P<0.01, significant difference compared to control