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Stability Data for propranolol hydrochloride microballoons at different temperatures.
| S.No | Sampling interval (days) | % Residual Drug Content Mean±S.D. (n=3) | Physical appearance | ||||
|---|---|---|---|---|---|---|---|
| 4±0.5°C | Room temp. | 40±0.5°C & 75% RH | 4±0.5°C | Room temp. | 40±0.5°C & 75% RH | ||
| 1 | 15 | 99.64±0.11 | 99.38±0.12 | − | + | + | − |
| 2 | 30 | 99.08±0.07 | 98.77±0.15 | − | + | + | − |
| 3 | 45 | 98.67±0.09 | 98.22±0.11 | − | + | + | − |
| 4 | 60 | 98.28±0.12 | 97.61±0.09 | − | + | + | − |
| 5 | 75 | 97.89±0.06 | 97.04±0.14 | − | + | + | − |
| 6 | 90 | 97.51±0.08 | 96.48±0.08 | − | + | + | − |
+ No change,Clump formation
