Table 4.

Categorized frequency of AEs; number (%) of patients with AEs.

Very common (>10%)
Transient Increase in serum creatinin) 2 consecutive times)
>33% of baseline level	96 (23.58%)
>33% of baseline level AND >ULN*	58 (14.2%)
Common (1–10%)
More than 5 times increase in transaminases:	24 (5.89%)
Skin rash	6 (1.47%)
loss of appetite	6 (1.47%)
Proteinuria	5 (1.22%)
Uncommon (<1%)/Rare:<0.1%
Diarrhea	2 (0.49%)
Abdominal pain	2 (0.49%)
Blurred vision;vomiting; Epistaxis; headache; flank pain; progressive creatinin rise; thrombocytopenia; prolonged fever	1 (0.24%)

^*ULN= Upper Limit of Normal