Figure 2.

Correspondence analysis of gene gains of CCND1 and EGFR among progressor, non-progressor, and normal groups. (a) A 2-dimensional display indicated that high gene gain of CCND1 showed a close distance to 3, the progressors, indicating the similarity of their patterns of relative frequencies. (b) A 2-dimensional display indicated that any gene gain of EGFR showed an even closer distance to 3, the progressors (3): (1) normal, (2) non-progressors, (3) progressors; no gain = ≤ 2 copies of gene in > 90% of nuclei; low gain = 3 copies of gene in ≥ 10% and ≥ 4 copies of gene in < 10% of nuclei; high gain = ≥ 4 copies of gene in > 10% of nuclei, a ratio of gene to centromere ≥ 2, or ≥ 15 copies of gene per nuclei in ≥ 10% of nuclei scored.