Table 3.

Lung function changes after salbutamol and ipratropium bromide

Patient number	ΔFEV1 (% pred)	ΔFEV1 (% pred)	ΔVC (L)	ΔVC (L)	ΔR (kPa/L)	ΔR (kPa/L)	ΔspecR (kPa)	ΔspecR (kPa)
Lung function testing
1	4	6	0.22	0.37	−0.120	−0.260	−1.44	−1.59
2	0	1	0.23	−0.01	−0.161	0.089	−1.00	0.19
3	6	4	0.28	0.27	−0.479	−0.201	−2.06	−0.91
4	8	6	0.55	0.54	−0.560	−0.461	−4.46	−3.38
5	3	6	0.04	0.20	−0.171	−0.339	−0.89	−1.51
Average	4.2	3.6	0.26	0.27	−0.298	−0.234	−1.97	−1.44
	ΔVtot(%)	ΔVtot(%)	ΔVcent(%)	ΔVcent(%)	ΔVdist(%)	ΔVdist(%)	ΔRawtot(%)	ΔRawtot(%)	ΔRawcent(%)	ΔRawcent(%)	ΔRdist(%)	ΔRdist(%)
Functional imaging
1	18.1	8.3	9.9	3.7	38.8	19.9	−44	−19	−30	0	−54	−33
2	11.1	8.0	5.7	5.6	39.9	20.8	−55	−41	−15	−16	−68	−49
3	19.6	10.9	10.0	5.8	80.6	43.7	−63	−56	−8	−13	−82	−71
4	0.7	17.6	−3.0	5.4	15.8	67.5	−27	−64	24	0	−37	−77
5	9.4	4.5	6.8	0.9	15.9	13.7	−34	−31	−37	−34	−33	−30
Average	10.8	10.5	5.0	4.5	31.6	32.4	−47.6	−44.5	−17.7	−16.7	−57.2	−58.1

Abbreviations: FEV₁, forced expiratory volume in 1 second; VC, vital capacity; R, airway resistance; specR, specific airway resistance (corrected for lung volume R × FRC); V_tot, total volume of the segmented airways; V_centr, volume of the central airways until the third bifurcation; V_dist, volume of the distal airways from third to seventh bifurcation; R_awtot, airway resistance of all segmented airways; R_awcentr, airway resistance on the central airways until the third bifurcation; R_awdist, airway resistance of the distal airways from third to seventh bifurcation; % pred, percentage predicted.

Notes: Grey shading indicates changes after salbutamol; no shading indicates changes after ipratropium bromide.