Table 2.
Logistic regression analysis of selected SNPs on the risk of NHL among women in Connecticut, adjusted for age and race.
| Controls | % | Cases | % | OR | 95% CI | P | |
|---|---|---|---|---|---|---|---|
| ADAM19 rs11466782 (IVS14-152 A>G) | |||||||
| AA | 445 | 85 | 341 | 76 | 1 | ||
| AG | 77 | 15 | 101 | 23 | 1.76 | 1.26–2.45 | 0.0009 |
| GG | 3 | 1 | 6 | 1 | 2.65 | 0.66–10.71 | 0.17 |
| AG/GG | 80 | 15 | 107 | 24 | 1.79 | 1.29–2.48 | 0.0004 |
| Trend | 1.73 | 1.28–2.35 | 0.0004 | ||||
| ICAM3 rs2304240 (Ex2-35 G>A) | |||||||
| GG | 349 | 66 | 335 | 75 | 1 | ||
| AG | 154 | 29 | 107 | 24 | 0.73 | 0.55–0.98 | 0.04 |
| AA | 22 | 4 | 6 | 1 | 0.29 | 0.11–0.72 | 0.01 |
| AG/AA | 176 | 34 | 113 | 25 | 0.68 | 0.51–0.90 | 0.01 |
| Trend | 0.67 | 0.52–0.86 | 0.002 | ||||
| PTGDR rs708486 (IVS1-478 A>G) | |||||||
| AA | 163 | 31 | 168 | 38 | 1 | ||
| AG | 252 | 48 | 215 | 48 | 0.80 | 0.60–1.06 | 0.12 |
| GG | 109 | 21 | 65 | 15 | 0.55 | 0.38–0.81 | 0.002 |
| AG/GG | 361 | 69 | 280 | 63 | 0.72 | 0.55–0.95 | 0.02 |
| Trend | 0.75 | 0.63–0.90 | 0.002 | ||||