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. Author manuscript; available in PMC: 2012 Dec 8.
Published in final edited form as: Cancer Lett. 2011 Jul 22;311(2):177–186. doi: 10.1016/j.canlet.2011.07.015

Fig. 4.

Fig. 4

Effects of VPA on cPAcP protein expression and ErbB-2 tyrosyl phosphorylation. LNCaP C-81 cells were plated in three cell dinsities (0.3, 0.5 and 1×106 cells/T25) in regular medium for 2 days and then treated with 1 mM VPA for 48 hr. The cells were harvested and the total protein was subjected to western blot analyses of functional proteins expression. VPA effects on cPAcP protein expression, ErbB-2 phosphorylation at Tyr1221/2 and Tyr1248, histone H3 and H4 acetylation and methylation, JNK and p38 phosphorylation, Bcl-2 and Bax protein levels. β-Actin was detected as a loading control. The data shown is a representative from three sets of independent experiments.