Skip to main content
. 2011 Dec 6;6(12):e28159. doi: 10.1371/journal.pone.0028159

Figure 7. Effect of CBD in rectal biopsies of patients with ulcerative colitis (UC) in the remission phase.

Figure 7

(A) shows the effect of CBD on glial activation evaluated as S100B protein expression. Western blot and relative densitometric analysis evidenced that CBD significantly and in a concentration dependent manner reduced LPS- induced S100B. (B) shows the effect of CBD on LPS + INF-γ induced iNOS protein expression and (C) nitrate production. Results are expressed as mean ± SEM of 3 experiments ***p<0.001 vs. CTR; °p<0.05, °°°p<0.001 vs. LPS+INF-γ.