Table 1.
Zoxazolamine paralysis test
| SRC-3+/+ | SRC-3+/− | SRC-3−/− | ||||
|---|---|---|---|---|---|---|
| Control | 8/15 | recovered < 8h | 1/18 | recovered < 8h | / | |
| 4/15 | recovered <12h | 6/18 | recovered <12h | / | ||
| 1/15 | recovered <24h | 4/18 | recovered <24h | / | ||
| 2/15 | died | 7/18 | died | 6/6 | died | |
| TCPOBOP | 18/18 | not paralyzed | 3/15 | not paralyzed | 3/9 | not paralyzed |
| / | 11/15 | recovered< 8h | 5/9 | recovered< 8h | ||
| / | 1/15 | died | 1/9 | died | ||
Mice were pretreated with a single dose of corn oil or TCPOBOP for 72 h, then mice were given a single i.p. injection of zoxazolamine, duration of paralysis was recorded after mice were able to right their bodies repeatedly.