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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Sep 15;4(12):1953–1960. doi: 10.1158/1940-6207.CAPR-11-0282

Table 2.

Risk of breast cancer by p16 expression in AH

Percent Cells
Positive for p16		 N Events Expected
Events		 SIR (95% CI)1 P-value2
0.88
0 80 18 4.2 4.24 (2.67 – 6.73)
1–10 78 12 3.5 3.45 (1.96 – 6.08)
11–50 45 11 2.6 4.15 (2.30 – 7.50)
51+ 30 6 1.7 3.52 (1.58 – 7.84)
1

Standardized incidence ratios and corresponding 95% confidence intervals, comparing the observed number of breast cancer events to those expected based on incidence rates from Iowa SEER data. Analyses account for the effects of age and calendar period.

2

Test for heterogeneity of the standardized incidence ratio across staining levels.