Table 1.

Comparison of phenotypes of mature dendritic cells (DCs) cultured with azithromycin (AZM)

Surface antigen	Control	AZM75 (d6) (P-value)*	AZM50 (d0,3,6) (P-value)*
CD 40	296 ± 56	141 ± 84 (0·01)	143 ± 36 (0·001)
CD 80	211 ± 69	175 ± 93 (0·50)	157 ± 31 (0·16)
CD 86	1846 ± 634	1682 ± 677 (0·70)	830 ± 277 (0·02)
MHC II	3320 ± 792	1781 ± 598 (0·01)	1654 ± 572 (0·007)

Data are presented as mean fluorescence intensity plus or minus standard deviation values of five independent experiments. AZM was added at graded concentration and timing; 75 µg/ml on day 6 and 50 µg/ml on days 0, 3 and 6.

^*P-value relative to results obtained with control. MHC: major histocompatibility complex.