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. Author manuscript; available in PMC: 2011 Dec 7.
Published in final edited form as: Sci Transl Med. 2011 Jul 6;3(90):90ra60. doi: 10.1126/scitranslmed.3002193

Fig. 6.

Fig. 6

Exposure of macrophages to CXCL5 produced an increase in intracellular Ca2+ concentration ([Ca2+]i). (A to D) Macrophages in which application of ATP (25 μM) produced a change in [Ca2+]i [as seen in (D)] were included in the analysis (thus excluding dead or nonfunctional cells). CXCL5 at a dose of 100 nM increased [Ca2+]i in a number of cells as indicated by the red arrows (C). (E) The percentage of cells responding to 100 nM CXCL5 was significantly larger than after vehicle treatment (E) (Kruskal-Wallis one-way ANOVA on ranks, n = 3 to 6 independent experiments with at least 100 cells per concentration, data are presented as mean% ± SEM). (F and G) Representative response traces of a single cell for macrophages (F) and DRG neurons (G).