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. 2011 May 26;122(2):137–153. doi: 10.1007/s00401-011-0839-6

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© The Author(s) 2011

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Fig. 6 — Histological features of FTLD-FUS molecular pathologies. Features of aFTLD-U, including striking striatal atrophy (a), neuronal cytoplasmic inclusions (NCI) (b) and vermiform neuronal intranuclear inclusions (c) with FUS immunohistochemistry. Features of NIFID, including internexin positive NCI (note weak cytoplasmic staining in pyramidal neurons) (d) and FUS positive NCI in cortex with FUS immunohistochemistry (e). Features of BIBD with juvenile motor neuron disease, including large basophilic cytoplasmic inclusions (f) that are positive with FUS immunohistochemistry (g)