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. 2011 Oct 5;96(12):E1963–E1972. doi: 10.1210/jc.2011-1408

Fig. 1.

Fig. 1.

Plasma kisspeptin IR and serum reproductive hormone levels after iv bolus injection of kisspeptin-10 to healthy male volunteers. A–D, Time profiles for plasma kisspeptin IR (A) and changes in serum LH (B), FSH (C), and testosterone (D) during 4 h after iv bolus injection of saline or kisspeptin-10 to healthy male volunteers (n = 4–5 per group). For 10 nmol/kg vs. saline: ψ, P < 0.05; ψψ, P < 0.01; ψψψ, P < 0.001. For 3 nmol/kg vs. saline: λ, P < 0.05; λλλ, P < 0.001. For 1 nmol/kg vs. saline: Δ, P < 0.05; ΔΔΔ, P < 0.001. E–H, AUC for plasma kisspeptin IR (E) and changes in serum LH (F), FSH (G), and testosterone (H) during 4 h after iv bolus injection of saline or kisspeptin-10 to healthy male volunteers (n = 4–5 per group). *, P < 0.05; **, P < 0.01; ***, P < 0.001. T, Testosterone. Data are shown as mean ± sem.