Table 1.
Parameters for pre- and postsurgery weight loss profiles, duration of weight loss, and late-onset weight regain (means ± sem)
| Reference | I251L | V103I | P value (one way ANOVA) | |
|---|---|---|---|---|
| Weight at initial visit (top plateau) (%)a | 108 ± 0.1 | 109 ± 0.7 | 107 ± 0.7 | 0.2 |
| Weight at nadir (bottom plateau) (%)a | 72 ± 0.1 | 65 ± 0.5c | 73 ± 0.6 | <0.0001 |
| Total weight loss (% kilograms at surgery) | 36 | 44 | 34 | |
| Months to weight nadira | 10 | 13 | 9 | |
| Slope from weight nadir (9–13 to 36 months)b | 0.018 | −0.072 | 0.158 | 0.4 |
Differences were determined using one-way ANOVA.
a
Parametes are from Hill regression global-fitting parameters.
b
Parametes are from linear fit.
c
Significance levels after Bonferroni's multiple comparisons post hoc, P < 0.0001 vs. reference.