Fig. 2.

(Top) The process of generating activity histograms and range indices from raw recording traces: raw current trace data obtained from electrophysiological recording of a large compound library were processed, and activity measurements of interest, for example, tail current inhibition, were calculated. Discretization and index construction are applied to generate histograms and range indices for efficient data exploration. (Bottom) Web interface for exploring data by activities: end users can first select an activity of interest (Step 1); the corresponding activity histogram presents an interactive distribution of the activity, which allows users to select a range of interest via mouse (Step 2); the Web interface then immediately displays the number of compounds whose activities fall into the selected range. Users can list these results in a tabular view by clicking the indicated button (Step 3).