Fig. 2.

Activation of MAPK signaling by different C. albicans cell wall mutants. Different C. albicans cell wall mutants, the parent strains (CAI4 and BWP17), and wild-type strain (SC5314) were added to TR146 oral epithelial cells under standard culture conditions for 2 h. Total protein was isolated, and phosphorylation of MKP1 and induction of c-Fos were assessed. Bands are shown relative to an α-actin loading control. A fungal/epithelial cell MOI of 10:1 was used. Data are representative of three independent experiments.