Table 3.
Target and parameter | FC | P value |
---|---|---|
S100A7 | ||
Gender (female) | 0.68 | 0.003 |
Age (yr) | 1.04 | 0.11 |
Follicular trachoma (F2/F3) | 2.39 | <0.0001 |
Bacterial infection | 1.37 | 0.03 |
IL1B | ||
Gender (female) | ||
Age (yr) | 0.96 | 0.13 |
Follicular trachoma (F2/F3) | ||
Bacterial infection | 1.22 | 0.16 |
IL17A | ||
Gender (female) | 1.15 | 0.18 |
Age (yr) | 0.92 | <0.0001 |
Follicular Trachoma (F2/F3) | 2.53 | <0.0001 |
Bacterial infection | 1.83 | <0.0001 |
IL23A | ||
Gender (female) | 0.86 | 0.04 |
Age (yr) | ||
Follicular trachoma (F2/F3) | 1.17 | 0.17 |
Bacterial infection | 1.22 | 0.02 |
CXCL5 | ||
Gender (female) | ||
Age (yr) | 0.94 | 0.06 |
Follicular trachoma (F2/F3) | 3.40 | <0.0001 |
Bacterial infection | 1.64 | 0.008 |
CCL18 | ||
Gender (female) | ||
Age (yr) | 0.93 | 0.0004 |
Follicular trachoma (F2/F3) | 2.55 | <0.0001 |
Bacterial infection | 2.05 | <0.0001 |
NLRP3 | ||
Gender (female) | ||
Age (yr) | 0.98 | 0.02 |
Follicular trachoma (F2/F3) | ||
Bacterial infection | 1.19 | 0.004 |
KLRD1 | ||
Gender (female) | ||
Age (yr) | 0.91 | <0.0001 |
Follicular trachoma (F2/F3) | ||
Bacterial infection | 1.42 | <0.0001 |
TLR2 | ||
Gender (female) | 0.95 | 0.19 |
Age (yr) | 0.99 | 0.15 |
Follicular trachoma (F2/F3) | 1.16 | 0.02 |
Bacterial infection | 1.11 | 0.02 |
CTGF | ||
Gender (female) | ||
Age (yr) | 0.97 | 0.03 |
Follicular trachoma (F2/F3) | 2.04 | <0.0001 |
Bacterial infection | 1.20 | 0.04 |
MMP9 | ||
Gender (female) | ||
Age (yr) | ||
Follicular trachoma (F2/F3) | 0.82 | 0.04 |
Bacterial infection |
Terms were retained in the model if their P value was <0.2, by likelihood ratio testing. FC, fold changes, which were derived from the models. The specific comparisons within these terms of the model were female versus male, age as a continuous variable in years, follicular trachoma (F2 or F3) versus no follicular trachoma (F0 or F1), and bacterial infection versus no bacterial infection. Using the Bonferroni correction for multiple comparisons, the critical significance threshold level is a P value of <0.0016.