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Vaccine-induced protection against wild-type S. dysenteriae 1 challenge
| Vaccine strain | Vaccine dose (CFU) | Challenge dose (CFU) | No. of animals protecteda/total no. of animals |
|---|---|---|---|
| CVD 1255 | 109 | 108 | 4/4 |
| CVD 1256 | 109 | 107 | 7/7 |
| 109 | 108 | 13/13 | |
| 109 | 109 | 3/4 | |
| CVD 1257 | 109 | 108 | 8/8 |
| CVD 1255(pOmpC-StxB) | 109 | 108 | 8/8 |
| CVD 1255(pTrc-StxB) | 109 | 108 | 6/6 |
| None (PBS) (control) | 108 | 0/9 |
Protection against full-blown keratoconjunctivitis (score of 4) at any time point postchallenge.
