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Colonization of mouse spleens and livers by χ3761 and its isogenic mutants, and mouse spleen weights. Shown are spleen (A, B) and liver (C, D) colonization by the indicated strains in BALB/c mice at 3 and 6 days postinoculation. (E) Spleen weights following use of the indicated strains in BALB/c mice at 6 days postinoculation. The horizontal lines represent the means, and error bars indicate the means ± SEM. ***, P < 0.001; **, P < 0.01; *, P < 0.05.
