Table 2.
Strain | Genotype | MIC (mg/ml) |
Motility (mm)b | LD50 (CFU)c | |
---|---|---|---|---|---|
DOCa | Polymyxin B | ||||
χ8573 | ΔmsbB48 | 6.25 | <0.032 | 41.5 ± 2.5 | 4.5 × 105 |
χ11165 | ΔmsbB48 ΔpagL7 | 6.25 | <0.032 | 42 ± 2 | 7 × 105 |
χ9908 | ΔmsbB48 ΔpagP8 | 6.25 | <0.032 | 32 ± 2 | 2.4 × 105 |
χ9949 | ΔmsbB48 ΔlpxR9 | 3.1 | <0.032 | 38.5 ± 2.5 | 1.4 × 105 |
χ11065 | ΔmsbB48 ΔpagL7 ΔpagP8 ΔlpxR9 | 6.25 | <0.032 | 36 ± 1 | 1.4 × 105 |
χ3761 | Wild-type UK1 | 6.25 | 0.59 | 40.5 ± 0.5 | 1.3 × 104 |
DOC, deoxycholate (bile salt).
Colony diameter in mm after 7 h of growth on the LB agar plate.
The data are based on probit analysis.