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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2011 Sep;70(9):799–810. doi: 10.1097/NEN.0b013e31822c09bc

Table 5.

Correlations of GABAA Receptor Autoradiography with Different 5-HT Markers in SIDS Cases and Controls in Dataset of Stage 2.

Correlation between
GABA autoradiography and
SIDS All Controls
N Correlation p-value N Correlation p-value
5-HT1A
ARC 23 0.48 0.024 7 −0.53 0.280
NTS 24 0.48 0.021 6 0.66 0.220
HG 24 0.05 0.820 6 −0.19 0.760
MAO 25 0.33 0.120 5 −0.36 0.640
GC 24 0.18 0.420 7 0.61 0.200
PGCL 24 0.31 0.140 7 0.81 0.052
IRZ 23 0.02 0.940 7 0.46 0.350
DAO 14 0.42 0.160 5 0.93 0.066
ROB 24 0.15 0.480 7 0.94 0.005
5-HT
ROB 23 0.24 0.270 7 0.003 0.990
GC 23 0.13 0.550 7 0.39 0.440
PGCL 23 0.28 0.200 7 0.05 0.920
TPH2
ROB 22 0.15 0.510 7 −0.51 0.300

5-HT1A receptor determined by tissue receptor autoradiography; 5-HT level determined by high performance liquid chromatography; and tryptophan hydroxylase (TPH2) determined by Western blotting (10).

Abbreviations: ARC, arcuate nucleus; NTS, nucleus of the solitary tract; HG, hypoglossal nucleus; MAO, medial accessory olive; GC, gigantocellularis; PGCL, paragigantocellularis lateralis; IRZ, intermediate reticular zone; DAO, dorsal accessory olive; ROB, raphé obscurus