Table 5.
Correlation between GABA autoradiography and |
SIDS | All Controls | |||||
---|---|---|---|---|---|---|---|
N | Correlation | p-value | N | Correlation | p-value | ||
5-HT1A | |||||||
ARC | 23 | 0.48 | 0.024 | 7 | −0.53 | 0.280 | |
NTS | 24 | 0.48 | 0.021 | 6 | 0.66 | 0.220 | |
HG | 24 | 0.05 | 0.820 | 6 | −0.19 | 0.760 | |
MAO | 25 | 0.33 | 0.120 | 5 | −0.36 | 0.640 | |
GC | 24 | 0.18 | 0.420 | 7 | 0.61 | 0.200 | |
PGCL | 24 | 0.31 | 0.140 | 7 | 0.81 | 0.052 | |
IRZ | 23 | 0.02 | 0.940 | 7 | 0.46 | 0.350 | |
DAO | 14 | 0.42 | 0.160 | 5 | 0.93 | 0.066 | |
ROB | 24 | 0.15 | 0.480 | 7 | 0.94 | 0.005 | |
5-HT | |||||||
ROB | 23 | 0.24 | 0.270 | 7 | 0.003 | 0.990 | |
GC | 23 | 0.13 | 0.550 | 7 | 0.39 | 0.440 | |
PGCL | 23 | 0.28 | 0.200 | 7 | 0.05 | 0.920 | |
TPH2 | |||||||
ROB | 22 | 0.15 | 0.510 | 7 | −0.51 | 0.300 |
5-HT1A receptor determined by tissue receptor autoradiography; 5-HT level determined by high performance liquid chromatography; and tryptophan hydroxylase (TPH2) determined by Western blotting (10).
Abbreviations: ARC, arcuate nucleus; NTS, nucleus of the solitary tract; HG, hypoglossal nucleus; MAO, medial accessory olive; GC, gigantocellularis; PGCL, paragigantocellularis lateralis; IRZ, intermediate reticular zone; DAO, dorsal accessory olive; ROB, raphé obscurus