Table 2.
Sensitivity, specificity, PPV, and NPV of the BG assay at different cutoff levels
Cutoff (pg/ml) | No./totala |
Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
---|---|---|---|---|---|---|
Above cutoff (cases) | Below cutoff (controls) | |||||
>10 | 92/100 | 11/52 | 92 | 21 | 69.2 | 57.9 |
>20 | 89/100 | 25/52 | 89 | 48 | 76.7 | 69.4 |
>40 | 87/100 | 30/52 | 87 | 58 | 79.8 | 69.8 |
>60 | 82/100 | 39/52 | 82 | 75 | 86.3 | 68.4 |
>80 | 79/100 | 43/52 | 79 | 83 | 89.8 | 67.2 |
>100 | 73/100 | 46/52 | 73 | 88 | 92.4 | 63.0 |
>120 | 65/100 | 46/52 | 65 | 88 | 91.5 | 56.8 |
>140 | 64/100 | 48/52 | 64 | 92 | 94.1 | 57.1 |
>160 | 62/100 | 51/52 | 62 | 98 | 98.4 | 57.3 |
Cases, patients with proven or possible candidemia; controls, patients with candidemia excluded.