Table 4.

Parameters obtained from ROC analysis of antibody responses to M. tuberculosis-specific antigens

Antigen	AUCa	SEMb	95% CIc	Positive likelihood ratio	Cutoff	Sensitivity (%)	Specificity (%)
PPD	0.897	0.025	0.849–0.945	53.24	0.052	59.15	98.89
OT	0.935	0.018	0.901–0.970	51.97	0.232	57.75	97.78
Ag85b	0.947	0.021	0.905–0.986	67.18	0.166	74.65	98.89
MPT64L	0.912	0.020	0.877–0.957	53.24	0.087	59.15	98.89
U1/TPX	0.878	0.029	0.820–0.935	39.30	0.102	43.66	98.89
Ag16kDa	0.877	0.028	0.822–0.932	31.69	0.208	33.80	98.89
TB16.3	0.719	0.044	0.632–0.805	40.56	0.070	45.07	98.89
Ag38kDa	0.907	0.025	0.860–0.957	44.37	0.242	49.30	98.89
Ag14kDa	0.836	0.031	0.774–0.899	39.30	0.122	43.66	98.89
CFP10	0.973	0.010	0.954–0.992	64.65	0.043	71.83	98.89
ESAT-6	0.846	0.035	0.781–0.916	60.85	0.118	67.61	98.89
CFP10-ESAT-6	0.910	0.023	0.865–0.954	59.58	0.075	66.20	98.89

^aAUC, area under the curve.

^bSEM, standard error of the mean.

^cCI, confidence interval.