Table 2.

Pharmacokinetic parameters for ABZSO and ABZSO₂ obtained in plasma and cysts^a

Pharmacokinetic parameter	Value for drug
	Plasma		Cysts
	ABZSO	ABZSO2	ABZSO	ABZSO2
AUC0–t (μg·h/ml[g]b)	4.40 ± 0.4 A	0.70 ± 0.2 A	1.50 ± 0.1 B	0.30 ± 0.1 C
Cmax (μg/ml[g]c)	2.60 ± 0.5 A	0.40 ± 0.1 B	0.50 ± 0.1 B	0.10 ± 0.0 C
Tmax (h)	0.50 ± 0.1 A	0.50 ± 0.1 A	1.00 ± 0.0 A	1.00 ± 0.0 A
Dp	5 min–6 h	5 min–4 h	5 min–6 h	5 min–4 h

^aSee footnote a of Table 1 for abbreviations. Different letters next to values indicate statistical differences in the pharmacokinetic parameter (P < 0.05). Values are means ± SD for drug parameters after oral administration of ABZ to mice (5 mg/kg).

^bPlasma AUC is expressed as μg·h/ml and cyst AUC as μg·h/g.

^cPlasma C_max is expressed in μg/ml and cyst C_max in μg/g.