Fig. 1.

Growth inhibition of A. fumigatus by cells exposed to azoles. Wells contained either A549 cells exposed to antifungals for 4 h or free drug at the indicated concentrations. These wells were then infected with AF293 conidia. Photographs were taken 48 h postinfection. No growth inhibition was observed with cells exposed to voriconazole even at higher concentrations up to 128 μg/ml (data not shown). Only posaconazole- and itraconazole-exposed cells were able to inhibit fungal growth.