Table 2.
Amino acid differences between Cyp51A from A. fumigatus and A. lentulusb
| Amino acid | A. fumigatus | A. lentulus |
|---|---|---|
| Pro3 | P3 (CCG) | P3S (TCG) |
| Trp6 | W6 (TGG) | W6L (TTG) |
| Met11 | M11 (ATG)a | M11T (ACG)a |
| Val15 | V15 (GTG) | V15M (ATG) |
| Ala18 | A18 (GCA) | A18V (GCA) |
| Fhe29 | F29 (TTT)a | F29Y (TAC)a |
| Ser49 | S49 (AGT) | S49N (AAT) |
| Leu67 | L67 (AAG) | K67R (AGG) |
| Asp161 | D161 (GAT) | D161N (AAT) |
| Arg171 | R171 (CGG) | R171Q (CAG) |
| Met172 | M172 (ATG) | M172V (GTG) |
| Asp255 | D255 (GAC) | D255G (GGA) |
| Cys270 | C270 (TGC) | C270S (AGC) |
| Lys314 | K314 (AAA) | K314Q (CAG) |
| Ala330 | A330 (GCC) | A330I (ATT) |
| Ser335 | S335 (AGT) | S335N (AAT) |
| Phe337 | P337 (CCT)a | P337S (TCT)a |
| His352 | H352 (CAT)a | H352Q (CAG)a |
| Ile354 | I354 (ATT) | I354V (GTT) |
| Ile360 | I360 (ATT) | I360L (CTT) |
| Ile367 | I367 (ATC) | I367L (CTC) |
| Met383 | M383 (ATG) | M383V (GTG) |
| Thr420 | T420 (ACT) | T420A(GCC) |
| Leu464 | L464 (CTT) | L464I (ATT) |
| Glu488 | E488 (GAA) | E488D (GAT) |
| Gly505 | G505 (GGC) | G505R (CGC) |
a
Polymorphisms between strains of A. lentulus.
b
Amino acid numbers are the same for both species.