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Infant TFV PK parametersa
| PK parameter | Value (range) for all infants (n = 16) |
|---|---|
| Median TFV AUC (ng·h/ml) | 1,841 (883–7,931) |
| Median Cmax (ng/ml) | 101 (40–621) |
| Median tmax (h) | 4.0 (3.8–23.8) |
| Median t1/2 (h) | 16.9 (8.5–27.0) |
| Median C24 (ng/ml) | 46 (17–120) |
| Median C36 (ng/ml) | 30b (15-78) |
Observed following 4-mg/kg TDF administration to infants.
n = 14.
