Table 1.
Strains and IC90 of Ga-Cit and Ga-DFOB
| Strain | Origin | IC90 (μM) of: |
|||
|---|---|---|---|---|---|
| Ga-Cit (Iso-Sensitest) | Ga-DFOB (Iso-Sensitest) | Ga-Cit (HHW) | Ga-DFOB (HHW) | ||
| Clinical isolates of Pseudomonas aeruginosa | |||||
| 9806/93 | W, NUH | 160 | 640 | 20 | 80 |
| 9791/93 | W, NUH | 80 | 320 | 20 | 40 |
| 9704/93 | W, NUH | 160 | 640 | 40 | 640 |
| 48/94 | W, NUH | 80 | 320 | 20 | 80 |
| 10243/93 | W, NUH | 160 | 640 | 20 | 80 |
| 10031/93 | W, NUH | 160 | 640 | 40 | 80 |
| 9962/93 | C/P, NUH | 80 | 320 | 20 | 40 |
| 9960/93 | C/P, NUH | 80 | 320 | 20 | 40 |
| 10140/93 | W, NUH | 160 | 640 | 20 | 160 |
| 7444/93 | W, NUH | 80 | 160 | 20 | 40 |
| 9870/93 | W, NUH | 160 | 320 | 20 | 40 |
| 8046/93 | W, NUH | 320 | 640 | 40 | 80 |
| 76/94 | C/P, NUH | 160 | 640 | 40 | 80 |
| 71/94 | C/P, NUH | 160 | 1,280 | 40 | 320 |
| 1824 | CF, DH(39) | 640 | 640 | 40 | 80 |
| 1956 | CF, DH(39) | 80 | 160 | 20 | 40 |
| 3308 | CF, DH(39) | 80 | 640 | 20 | 80 |
| 2988 | CF, DH(39) | 160 | 320 | 20 | 40 |
| 2152 | CF, DH(39) | 320 | 1,280 | 40 | 160 |
| 1949 | CF, DH(39) | 160 | 320 | 40 | 80 |
| Clinical isolates of coagulase-negative Staphylococcus epidermidis | |||||
| 38. 04-77651 | BB, NUH | >5,120 | 5,120 | 2,560 | 1,280 |
| 39. 04-139122 | BB, NUH | 2,560 | 1,280 | 1,280 | 640 |
| 40. 05-95325 | BB, NUH | 2,560 | 1,280 | 1,280 | 640 |
| 41. 04-26895 | BB, NUH | 5,120 | 5,120 | 2,560 | 2,560 |
| 42. 0691964 | BB, NUH | 5,120 | 5,120 | 2,560 | 1,280 |
| 45. 06-87106 | BB, NUH | 2,560 | 1,280 | 1,280 | 1,280 |
| 132. 2008-02-3902 | C/P, NUH | 5,120 | 2,560 | 2,560 | 640 |
| 137. 2008-02-2068 | C/P, NUH | 2,560 | 2,560 | 2,560 | 640 |
| 135. 2008- 03-7703 | C/P, NUH | 2,560 | 2,560 | 2,560 | 640 |
| Reference strains | |||||
| P. aeruginosa PAO1 | DSMZ | 160 | 320 | 40 | 80 |
| P. aeruginosa 14 | MW | 160 | 320 | 20 | 40 |
| P. aeruginosa 17619 | CCUG | 80 | 320 | 20 | 40 |
| S. epidermidis 1621 | CCUG | 2,560 | 2,560 | 2,560 | 1,280 |
| S. epidermidis 43038 | CCUG | >5,120 | 2,560 | 1,280 | 640 |
| S. aureus Newman | ES | 5,120 | 2,560 | 320 | 640 |
| S. aureus Newman Δfur | ES | 5,120 | 5,120 | NG | NG |
| S. aureus 1800 | CCUG | 5,120 | 5,120 | 640 | 320 |
| S. aureus 1828 | CCUG | 2,560 | 2,560 | 5,120 | >5,120 |
| S. aureus 10778 | CCUG | 2,560 | 2,560 | 5,120 | 5,120 |
| S. aureus 15915 | CCUG | 5,120 | 5,120 | 2,560 | 2,560 |
| S. aureus 42765 | CCUG | 5,120 | 5,120 | 5,120 | 5,120 |
| S. aureus MRSA16 | MW | >5,120 | 2,560 | 5,120 | 2,560 |
| S. aureus MRSA15 | MW | 5,120 | 5,120 | 5,120 | 5,120 |
| E. faecalis 9997 | CCUG | 1,280 | 1,280 | NG | NG |
| E. faecalis ATCC29212 | MW | 2,560 | 5,120 | NG | NG |
| K. pneumoniae 225 | CCUG | 1,280 | 2,560 | 1,280 | 2,560 |
| K. pneumoniae 10785 | CCUG | 2,560 | 2,560 | 1,280 | 1,280 |
| K. pneumoniae 38027 | CCUG | >5,120 | 5,120 | 5,120 | 2,560 |
| P. mirabilis 26767 | CCUG | 1,280 | 1,280 | 1,280 | 1,280 |
| E. coli 10979 | CCUG | >5,120 | >5,120 | 1,280 | 1,280 |
| E. coli 17620 | CCUG | 5,120 | >5,120 | 2,560 | 5,120 |
| E. coli UPEC 536 MP10:24 | SNW | 2,560 | 2,560 | 2,560 | 2,560 |
| V. cholerae A1 552 O1 ELTOR CTX+ | SNW | 1,280 | 1,280 | 2,560 | 1,280 |
| V. cholerae V:5 NONO1 0139 | SNW | 1,280 | 1,280 | 1,280 | 1,280 |
W, wound; BB, bone biopsy; CF, cystic fibrosis; C/P, catheter/prosthesis; NG, no growth; CCUG, culture collection, University of Gothenburg; SNW, Sun Nyunt Wai collection, Umeå University; MW, Martin Welch collection, University of Cambridge; DSMZ, Deutsche Sammlung von Mikroorganismen und Zellkulturen; ES, Erik Scaar collection, Vanderbilt University; NUH, Norrland University Hospital; DH, Didier Hocquet collection, Addenbrooke's Hospital.