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Efficacy of cyclopropyl carboxamides in the P. falciparum mouse model. (A) Dose-response relationship. Data are presented as the mean of three mice ± the standard error of the mean for log10 [percentage of parasitemias at day 7 after infection]. (B) Giemsa-stained blood smears from vehicle- and GSK2645947-treated mice. Blood samples were taken at day 7 after infection (2 cycles of parasite growth with drug exposure).
