Table 1.
Clinical, radiological, immunological, and real-time PCR results for patients with NCC
| Patient group and no. | Clinical signs | Cerebral radiology result | Epidemiology | Immunology resulta | Real-time PCR result (CTb) |
|---|---|---|---|---|---|
| Definitive NCCc | |||||
| P1 | Psychiatric and memory disorders, spatial disorientation, aphasia | 3 IPn lesions | Africa, 36 yr ago | Serum positive/CSF positive | Serum negative/CSF positive (36.38) |
| P2 | Headache, neck ache, nausea, vomiting | Multiple intraventricular lesions, ventricular dilatation, foramen of Monro obstruction | Central Africa, 21 yr ago | Serum positive/CSF positive | Serum negative/CSF positive (34.40) |
| P3 | Headache, nausea, vomiting | IP calcifications, hydrocephalus, aqueduct of Sylvius obstruction | Haiti, 7 yr ago | Serum positive/CFS positive | Serum negative/CSF1 negative, CSF2d positive (32.92) |
| P4 | Epilepsy, neuralgia, paresthesia | IP calcifications, hydrocephalus, arachnoiditis | Haiti, 22 yr ago | Serum positive/CSF positive | Serum negative/CSFe positive (31.60) |
| P5 | Epilepsy, headache, vomiting | 2 IP lesions, chronic meningitis | Cape Verde, 1 yr ago | Serum positive/CSF positive | Serum negative/CSF1 positive (29.3), CSF2f positive (21.25), CSF3g positive (23.32) |
| P6 | Epilepsy, confusion | Multiple IP lesions, hydrocephalus, vascularitis | Cape Verde, 20 yr ago | Serum positive/CSF positive | Serum negative/CSF1 positive (26.15), CSF2h positive (26.66), CSF3i positive (28.01), CSF4j positive (30.59), CSF5k positive (29.65), CSF6l positive (32.33) |
| Probable NCCc | |||||
| P7 | Headache, nausea, memory disorders, dysphasia, spatial disorientation, muscular cysticercosis | IP calcifications, parasagittal meningioma, then hydrocephalus, meningoencephalitis | Madagascar, 34 yr ago | Serum positive/CSF positive | Serum negative/CSF1 positive (39.20), CSF2m positive (30.99) |
| P8 | Headache, epilepsy | 4 IP lesions | Cape Verde, 2 mo ago | Serum positive/CSF positive | Serum negative/CSF negative |
| P9 | Headache, epilepsy | 1 IP lesion | India, 6 yr ago | Serum positive/CSF negative | Serum negative/CSF negative |
Immunoblotting was performed with the cysticercosis Western blot IgG kit (LDBio Diagnostics, France).
CT, cycle threshold.
NCC was categorized as definitive or probable according to the diagnostic criteria of Del Brutto et al. (5).
CSF drawn after external ventricular derivation (fluid derived via a ventriculoperitoneal shunt), 3 days after the first sample.
CSF drawn after external peritoneal derivation.
CSF drawn 3 months after the first sample.
CSF drawn 5 months after the first sample.
CSF drawn 1 month after the first sample.
CSF drawn 3 months after the first sample.
CSF drawn 3 1/2 months after the first sample.
CSF drawn 3 3/4 months after the first sample.
CSF drawn 4 months after the first sample.
CSF drawn 38 months after the first sample.
IP, intraparenchymal.