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rpoB mutations detected in the C. difficile isolates resistant to rifamycins
| Substitution | No. of isolates | Source (n) | Rifamycin susceptibilityb |
|---|---|---|---|
| H502N/R505K | 7 | ISS (7) | R |
| R505K | 6 | ISS (6) | R |
| S488Pa | 1 | ISS (1) | I |
| S498T,a R505K | 3 | ISS (3) | R |
| H502N | 2 | ISS (1), JGH (1) | I/R |
Mutation not previously described for C. difficile.
R, resistant; I, intermediate.
