Table 2.
Sensitivity of B. multivorans wild-type and PNAG-negative Mu5 (ΔpgaBC) biofilms to 250 μg/ml tobramycin
| Strain | Mean log10 CFU of biofilm-embedded cells/ml ± SD with: |
Log reduction due to tobramycin treatmenta | Pb | |
|---|---|---|---|---|
| No treatment (control) | Tobramycin | |||
| Wild type | 9.95 ± 0.27 | 6.7 ± 0.08 | 3.25 | 0.001 |
| Mu5 | 8.87 ± 0.13 | 3.77 ± 0.16 | 5.1 | <0.0001 |
a
Mean log density for untreated control minus the mean log density for corresponding tobramycin treatment.
b
Determined using two-tailed Student's t test with unequal variance.