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HPP disrupts VSV particles. Purified VSV was treated by high pressure at 550 MPa at 20°C for 8 min and 10 min separately. Treated and untreated virus particles were negatively stained with 1% ammonium molybdate and visualized by transmission electron microscopy. (A) Untreated VSV virions. (B) VSV particles treated with 550 MPa for 8 min. (C) VSV particles treated with 550 MPa for 10 min.
