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Effect of IFN-γ on airway inflammation and hyperresponsiveness. (A) Total cells present in BALF. (B) Leukocyte percentages before and after anti-IFN-γ treatment. (C) Penh levels. (D) M2R mRNA levels. (E) IFN-γ levels after anti-IFN-γ treatment. Values are expressed as means ± SD (n = 8/group). *, P < 0.05 versus the RSV group; **, P < 0.001 versus the RSV group with between 12.5 and 50 mg/ml methacholine.
