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. 2011 Dec;85(24):13333–13341. doi: 10.1128/JVI.05671-11

Fig. 5.

Fig. 5.

Comparison of the ability of CD8 (A) and CD4 (B) T cell subsets from cervical and blood samples from HIV-infected (n = 15) and uninfected (n = 39) women to produce IFN-γ and IL-2 after global stimulation with PMA-ionomycin. The magnitude of the response by CD45RA− CCR7+ CM, CD45RA− CCR7− EM, and CD45RA+ CCR7− TD cell subsets (based on the expression of phenotypic markers CD45RA and CCR7) were compared for each group using the Mann-Whitney U test, and P values of ≤0.05 were considered significant (*, P < 0.05; **, P < 0.005). All frequencies were adjusted for background by subtracting unstimulated cytokine production from PMA-ionomycin responses by each T cell subset.