Table II.
Longitudinal comparisons of prebronchodilator pulmonary function (spirometry) between groups of children from ages 5 through 8 y∗ with and without asthma
| Asthma† |
|||||
|---|---|---|---|---|---|
| No | Yes | Diff | 95% CI | P value | |
| n | 140 | 84 | |||
| FVC | 1.58 (0.02) | 1.58 (0.02) | 0.00 | (−0.05, 0.05) | .99 |
| FVC PP | 104 (1) | 104 (1) | 0 | (−3, 4) | .68 |
| FEV1 | 1.35 (0.02) | 1.33 (0.02) | −0.02 | (−0.07, 0.03) | .37 |
| FEV1 PP | 102 (1) | 100 (1) | −1 | (−5, 2) | .53 |
| FEV0.5 | 1.04 (0.02) | 1.00 (0.02) | −0.04 | (−0.08, 0.00) | .08 |
| FEF25-75 | 1.41 (0.04) | 1.31 (0.04) | −0.10 | (−0.20, 0.00) | .05 |
| PEFR | 2.76 (0.06) | 2.68 (0.06) | −0.08 | (−0.21, 0.05) | .22 |
| FEV1/FVC | 0.87 (0.01) | 0.85 (0.01) | −0.01 | (−0.03, 0.00) | .06 |
| FEV0.5/FVC | 0.67 (0.01) | 0.64 (0.01) | −0.02 | (−0.04, −0.01) | .01 |
FEF25-75, Forced expiratory flow at 25% to 75% of FVC; FEV1 PP, FEV1 percent predicted; FVC, forced vital capacity; FVC PP, FVC percent predicted; PEFR, peak expiratory flow rate.
∗
Longitudinal analyses for lung function obtained from children ages 5 through 8 y adjusted for age, race, gender, height, weight, asthma, passive smoke exposure, and age at the first occurrence of positive aeroallergen FEIA. Percent-predicted values adjusted for asthma, smoke, and FEIA only. Groups summarized by least-squares means (standard error).
†
Asthma defined at ages 6 and 8 y.