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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Immunol. 2011 Nov 7;187(11):5577–5586. doi: 10.4049/jimmunol.1101626

Figure 3. CD84 inhibits FcεRI-mediated cytokine secretion.

Figure 3

CD34+ peripheral blood-derived huMCs were sensitized overnight with biotinylated IgE and incubated with 5 µg/ml of biotinylated anti-CD84 (IgE/CD84) or isotype control (IgE/IC) or media (IgE) and then stimulated for 6 h with 1 µg/ml streptavidin (SA). IL-8 (A) and GM-CSF (B) production is represented. Results are representative of three independent experiments and are expressed as the mean +/− SD. Statistical significance (*p< 0.05, **p< 0.001) is relative to IgE/IC.