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Comparison of the structures of the Kl and Sc Scm3-Cse4-H4 and human HJURP-CENP-A-H4 complexes. The dashed open ovals indicate the regions that are occupied by DNA in the nucleosome structures. The dashed open squares indicate the regions that have similar structures. In the case of the Sc complex, this region is necessary and sufficient for specific recognition between Scm3 and Cse4/H4. The colored dashed lines represent the disordered regions.
