Table 1.

Tumors with loss of the NIRF gene showing COPA scores ranked in the top 5%

Tumor Type	Dataset Name	Gene Rank (top %)	COPA Score	Percentile	Log2 Copy Number Units	Reference
Glioblastoma	TCGA Brain 2	0.2	−52.222	10	−0.6271	48
	Beroukhim Brain	0.7	−2.448	25	−0.1022	52
	Kotliarov Brain	1.7	−2.593	25	−0.2363	53
Breast cancer	Haverty Breast	2.6	−2.412	25	−0.1757	54
	TCGA Breast 2	4.8	−15.540	10	−0.3507	55
Gastric cancer	TCGA Gastric	1.5	−18.207	5	−0.4362	55
Kidney cancer	Beroukhim Renal 2	1.5	−3.990	25	−0.1237	56
Chronic lymphocytic leukemia85	Gunnarsson Leukemia	0.6	−1.376	25	−0.0282	57
Lung cancer	Lu Lung	0.5	−4.510	5	−0.5203	58
	TCGA Lung 2	1.8	−11.671	10	−0.4022	55
	Sos Cell Line	0.4	−3.123	10	−0.5987	59
Mesothelioma	Brachmann Mesothelioma	1.4	−2.766	25	−0.2216	NA

Searches were carried out using the following Oncomine parameters: view mode, gene summary mode; gene, NIRF (UHRF2); analysis type, outlier analysis; data type, DNA. The thresholds were: p value, <1 × 10⁻⁸; gene rank, top 5%; fold change, 20.