Table 2.
Underexpressed genes in 9p24 in squamous cell lung carcinoma compared with normal tissue70
Gene Rank | Gene Symbol | Gene Name | Reporter ID | t-test | p value | Fold Change |
1 | NIRF/UHRF2 | Np95/ICBP90-like RING finger | 34036_at | −6.240 | 1.15E-07*** | −1.303 |
2 | KANK1 | KN motif and ankyrin repeat domains 1 | 37225_at | −4.681 | 9.58E-06*** | −1.557 |
3 | INSL4 | insulin-like 4 (placenta) | 34219_at | −3.944 | 1.08E-04*** | −1.244 |
4 | RLN1 | relaxin 1 | 35070_at | −4.049 | 1.24E-04*** | −1.189 |
5 | RANBP6 | RAN binding protein 6 | 32627_at | −3.075 | 0.00159** | −1.122 |
6 | MLANA | melan-A | 1051_g_at | −2.936 | 0.00294** | −1.182 |
7 | SLC1A1 | solute carrier family 1, member 1 | 38268_at | −2.308 | 0.0123* | −1.140 |
8 | KDM4C | lysine (K)-specific demethylase 4C | 34980_at | −2.317 | 0.0124* | −1.085 |
9 | KCNV2 | potassium channel, subfamily V, member 2 | 36339_at | −1.951 | 0.0283* | −1.099 |
10 | VLDLR | very low density lipoprotein receptor | 36873_at | −1.826 | 0.0365* | −1.204 |
Dataset from Talbot Lung, squamous cell lung carcinoma vs. normal.70 Reporter ID in Human Genome U95A-Av2 Array (Affymetrix); *p < 0.05, **p < 0.01, ***p < 0.001; n = 34.