Table 3.
T-test for beta differences by race for liver attenuation1 (in HU)
African Americans; N=505, number of families=204 | Caucasians; N=2214, number of families=503 | T-test for Beta difference by race | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Beta | SE | p | Beta | SE | p | Beta Difference | dfBD3 | SE | p | |
Sex (Male) | −0.13 | 0.98 | 0.68 | 0.56 | ||||||
Age (yrs) | 0.05 | 0.04 | 0.07 | 0.02 | ** | −0.02 | 2008 | 0.022 | 0.3 | |
Alcohol (grams/wk) | −0.01 | 0.01 | * | −0.02 | 0.003 | ** | 0.004 | 2008 | 0.004 | 0.4 |
Body Mass Index (kg/m2) | 0.01 | 0.13 | −0.37 | 0.08 | ** | 0.38 | 2008 | 0.09 | ** | |
Abdominal visceral adipose (cm3) | −0.03 | 0.01 | * | −0.02 | 0.004 | ** | −0.01 | 2008 | 0.005 | 0.1 |
Abdominal subcutaneous adipose (cm3) | −0.005 | 0.005 | 0.005 | 0.003 | ||||||
Triglycerides (mg/dl) | −0.003 | 0.005 | −0.02 | 0.002 | ** | 0.01 | 2008 | 0.003 | ** | |
HDL-Cholesterol (mg/dl) | 0.03 | 0.03 | −0.03 | 0.02 | † | 0.06 | 2008 | 0.02 | * | |
HOMA-IR2 | −0.62 | 0.11 | ** | −0.80 | 0.07 | ** | 0.18 | 2008 | 0.08 | † |
Adjusted for phantom and center. A standardized phantom contains material that simulates water (expected HU=0) as well as increasing densities of calcium (50, 100 and 200 mg of calcium). These concurrent phantom measures at water density were used to adjust and standardize the liver attenuation measurements.
HOMA-IR (homeostasis model of insulin resistance)= (fasting serum glucose [mg/L]* fasting serum insulin [mU/L]/405)
dfBD (degrees of freedom for beta difference)= (N − number of families − 2)
p<0.0001,
p<0.01,
p<0.05