TABLE 2.
Baseline characteristics of surgical patients included in the ABG substudy iso-work analysis classified as deflators and non-deflators.
Characteristic | Deflators N=24 |
Non-Deflators N=9 |
p-value |
---|---|---|---|
Age – yrs | 69 (64–72) | 66 (66–69) | 0.79 |
Female sex – no. (%) | 9 (38%) | 0 (0%) | 0.04 |
White race – no. (%) | 22 (92%) | 7 (78%) | 0.30 |
BMI – kg/m2 | 25.1 (23.7–28.2) | 27.5 (24.6–28.4) | 0.55 |
Pack years | 61 (47–90) | 40 (35–80) | 0.23 |
Upper lobe predominant distribution of emphysema on CT – no. (%) | 21 (88%) | 3 (33%) | 0.005 |
FEV1 % predicted* | 28 (24–33) | 29 (25–30) | 0.89 |
TLC % predicted* | 128 (113–135) | 133 (119–136) | 0.47 |
RV % predicted* | 201 (181–237) | 195 (180–228) | 0.79 |
DLCO % predicted† | 29 (23–39) | 28 (21–30) | 0.37 |
RV/TLC | 0.62 (0.59–0.67) | 0.52 (0.49–0.60) | 0.01 |
Room Air PaO2 – mmHg | 64 (55–77) | 55 (53–74) | 0.58 |
Room Air PaCO2– mmHg | 41 (38–43) | 40 (37–45) | 0.98 |
6 min walk distance – m | 422 (349–457) | 460 (422–486) | 0.24 |
Maximal workload – W | 43 (34–68) | 58 (45–67) | 0.24 |
O2 pulse – mL/beat | 7.7 (6.03–9.89) | 10.1 (7.96–12.36) | 0.06 |
Definition of abbreviations: BMI = body mass index; FEV1 = forced expiratory volume in one second, TLC = total lung capacity, RV = residual volume, DLCO = diffusing capacity of carbon monoxide Data presented as medians and interquartile ranges unless otherwise specified
Measurement obtained post-bronchodilator
Baseline DLCO was obtained prior to pulmonary rehabilitation; all other baseline pulmonary function measures were completed after pulmonary rehabilitation