Table 1.
Demographics, histologic, and cytogenetic findings in 20 benign skin and soft tissue mixed tumors/ myoepitheliomas.
| Case No. | Age (Yo) | Sex | Location | Tubular Diff | PLAG1 IHC (score/intensity) | PLAG1 FISH | EWSR1 Status* |
|---|---|---|---|---|---|---|---|
| 1 | 55 | F | Skin, foot | Y | 3+/strong | Pos (with interstitial Del) | UK |
| 2 | 70 | F | Skin, back | Y | 1+/intermediate | Ind | UK |
| 3 | 39 | M | Skin, chest wall | N | Ind | Pos (Unbal) | UK |
| 4 | 60 | M | Skin, upper arm | N | 0 | NP | UK |
| 5 | 36 | F | Skin, arm | N | 0 | Neg | UK |
| 6 | 84 | M | Skin, forehead | Y | 2+/strong | Pos (Unbal) | Neg |
| 7 | 0.5 | M | Skin, scalp | N | 0 | Neg | UK |
| 8 | 66 | F | Skin, lower leg | Y | 3+/strong | NP | Neg |
| 9 | 64 | F | Skin, scalp | Y | 3+/intermediate | Pos (Unbal) & copy gain | UK |
| 10 | 56 | F | Skin, scalp | Y | 3+/strong | Pos | UK |
| 11 | 32 | M | ST, ankle | N | 2+/faint | NP | Pos |
| 12 | 73 | F | ST, thigh | Y | 1+/intermediate | NP | Neg |
| 13 | 41 | M | ST, foot | N | Rare/intermediate | Ind | Neg |
| 14 | 53 | F | ST, abdominal wall | N | 0 | NP | UK |
| 15 | 34 | M | ST, thigh | N | 0 | NP | Neg |
| 16 | 58 | F | ST, groin | Y | 1+/intermediate | NP | Neg |
| 17 | 62 | M | ST, lower leg | Y | 3+/strong | Pos (?Inv) | Neg |
| 18 | 20 | M | ST, foot | N | 0 | Neg | Pos |
| 19 | 67 | F | ST, axilla | Y | 3+/strong | Pos | Neg |
| 20 | 52 | F | ST, foot | Y | 3+/strong | Pos (?Inv) | Neg |
Abbreviations: Del, deletion; Diff, differentiation; F, female; Ind, indeterminate; Inv, inversion; M, male; N, No; Neg, negative; NP, not performed; Pos, positive; ST, soft tissue; UK, status unknown; Unbal, unbalanced translocation; Y, yes; Yo, years old.
*
Information obtained from Antonescu et al., 2010.