Table 3.

Use of PiB PET to Distinguish Controls from MCI and MCI from AD dementia

Reference	HCa	MCIa	ADa	HC vs. MCIb	MCI vs. ADb
(Pike et al., 2007)	32	33	31	p<0.001	p<0.001
(Kemppainen et al., 2007)	14	13	0	p<0.01	n/a
(Forsberg et al., 2008)	6	21	27	ns	p<0.01
(Jack et al., 2008)	20	17	8	ns	p=0.004
(Li et al., 2008)	7	13	17	trend p=0.06	p<0.005
(Koivunen et al., 2008)	22	15	0	p<0.0001	n/a
(Mormino et al., 2009)	37	39	20	p=0.046	trend p=0.07
(Tolboom et al., 2009c)	13	11	14	p<0.05	p<0.0001
(Lowe et al., 2009)	20	23	13	ns	p<0.001
(Okello et al., 2009b)	38	31	0	p<0.01	n/a
(Forsberg et al., 2010)	0	21	37	n/a	p<0.001
(Devanand et al., 2010)	18	24	18	p=0.02	p<0.0001
(Rowe et al., 2010)	177	57	53	p<0.05	p<0.05

^aNumber of Healthy Control (HC), MCI or AD dementia subjects in the study.

^bP-value for comparison of healthy controls to MCI subjects or MCI to AD dementia.