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. 2011 Dec 8;4:14. doi: 10.3389/fneng.2011.00014

Figure 8.

Figure 8

Recordings of spontaneous fast monophasic positive action potentials (FMPP) generated by cultured hippocampal neurons grown on a PEI functionalized gMμEs based MEA for 10 days. (A) Spontaneous trains of FPMP generated by three neurons (one coupled to electrode 62, the second coupled to three electrodes 17, 36, and 27 and the third to electrode 38). The distance between electrodes 27 and 36 is approximately 40 μm. (B) The location of the electrodes that picked up the spike activity is depicted on a schematic layout of the MEA. (C) The potential recorded by electrodes 62, 17, and 38 in (A) are enlarged. (D) A 1-mV, 20 ms square calibration pulse delivered to the bathing solution and recorded by electrode 62.