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. 2011 Dec 8;4:14. doi: 10.3389/fneng.2011.00014

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Copyright © 2011 Fendyur, Mazurski, Shappir and Spira.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.

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Recordings of spontaneous long-lasting potentials (LLP) presumably generated by cultured glia cells grown on PEI functionalized gMμEs based MEA for 10 days. (A) Spontaneous synchronized LLPs recorded by seven gMμEs. Six gMμEs recorded synchronized monophasic negative going potentials (electrode number 64, 65, 74, 75, 76, and 84) while one electrode (85) recorded mirror image positive going potentials. (B) Enlargement of the mirror image LLPs recorded by electrodes 85 and 75. (C) A calibration pulse of 1 mV 20 ms. As recorded by electrode 85 (D) The location of the gMμEs that picked up the LLPs is depicted on a schematic layout of the MEA. Note that the cell generating these LLPs extends over an area of approximately 60 μm × 60 μm.