Table 2.
Treatment | Mechanism | Urinary phosphate | Serum phosphate | Serum calcium | Serum 1,25D | Tumoral calcinosis lesions |
---|---|---|---|---|---|---|
Dietary phosphate restriction | Decrease phosphate load | ↓ | ↓ | ↔ | ↑ ↔ | ↓ ↔ |
Phosphate binders | Decrease phosphate load | ↓ | ↓ | ↔ | ↑ ↔ | ↓ ↔ |
Acetazolamide | Increase phosphate excretion | ↑ | ↓ | ↔ | ↔ | ↓ ↔ |
Calcitonin | Increase phosphate excretion | ↑ | ↓in TC (but↑ in XLH) | ↔ ↓ | ↑ | ↓ ↔ |